v. 1. Nicomachean ethics. Politics. The Athenian Constitution. Rhetoric. On Poetics.--v. 2. Logic.--v. 3. Physics. Metaphysics. On the soul. Short physical treaties.--v. 4. On the heavens. On generation and corruption. Meteorology. Biological treatises.

Forty years’ experience as a bacterial geneticist has taught me that bacteria possess many cognitive, computational and evolutionary capabilities unimaginable in the first six decades of the twentieth century. Analysis of cellular processes such as metabolism, regulation of protein synthesis, and DNA repair established that bacteria continually monitor their external and internal environments and compute functional outputs based on information provided by their sensory apparatus. Studies of genetic recombination, lysogeny, antibiotic resistance and my own work on transposable elements revealed multiple (...) widespread bacterial systems for mobilizing and engineering DNA molecules. Examination of colony development and organization led me to appreciate how extensive multicellular collaboration is among the majority of bacterial species. Contemporary research in many laboratories on cell–cell signaling, symbiosis and pathogenesis show that bacteria utilise sophisticated mechanisms for intercellular communication and even have the ability to commandeer the basic cell biology of ‘higher’ plants and animals to meet their own needs. This remarkable series of observations requires us to revise basic ideas about biological information processing and recognise that even the smallest cells are sentient beings. (shrink)

Los estudios recientes sobre el pensamiento político de Unamuno han venido adscribiéndolo al liberalismo sin insertar su pensamiento en el desarrollo histórico del pensamiento liberal. Es por ello por lo que en este artículo acometemos una revisión del liberalismo de Unamuno, ubicando sus ideas en la historia del pensamiento liberal. Ello nos llevará a matizar las etiquetas políticas que se han puesto a Unamuno, así como a alcanzar las siguientes conclusiones: 1) Unamuno carecía de un conocimiento profundo del liberalismo según (...) éste se consolidó en la filosofía política de su tiempo; 2) su liberalismo oscila entre el liberalismo social y el liberalismo individualista, 3) propendiendo en los años treinta al liberalismo individualista de Mill y Spencer, precursor del liberal conservadurismo. (shrink)

This article discusses Descartes’s preferred focus on morally and theologically neutral subjects and points out the impact of this focus on the scientific status of theology. It does so by linking Descartes’s method to his transformation of the notion of substance. Descartes’s _Meditations_ centred around epistemological questions rather than non-human intelligences or the life of the mind beyond this world. Likewise, in his early works, Descartes consistently avoided referring to causal operators. Finally, having first redefined the notion of substance in (...) the _Principia,_ Descartes would completely abandon making use of this notion in his later years. Indeed, in contrast to many authors before and after him, Descartes never showed any interest in the long-established metaphysical interpretation of substances as being causal factors of natural change. With God, nature, and mind commonly serving as instances of substantial causality, Descartes’s philosophy had a huge impact on the place of God in science and discreetl. (shrink)

We performed an EEG graph analysis on data from 31 typical readers (22.27 ± 2.53 y/o) and 24 dyslexics (22.99 ± 2.29 y/o), recorded while they were engaged in an audiovisual task and during resting-state. The task simulates reading acquisition as participants learned new letter-sound mappings via feedback. EEG data was filtered for the delta (0.5–4 Hz), theta (4–8 Hz), alpha (8–13 Hz), and beta (13–30 Hz) bands. We computed the Phase Lag Index (PLI) to provide an estimate of the (...) functional connectivity between all pairs of electrodes per band. Then, networks were constructed using a Minimum Spanning Tree (MST), a unique sub-graph connecting all nodes (electrodes) without loops, aimed at minimizing bias in between groups and conditions comparisons. Both groups showed a comparable accuracy increase during task blocks, indicating that they correctly learned the new associations. The EEG results revealed lower task-specific theta connectivity, and lower theta degree correlation over both rest and task recordings, indicating less network integration in dyslexics compared to typical readers. This pattern suggests a role of theta oscillations in dyslexia and may reflect differences in task engagement between the groups, although robust correlations between MST metrics and performance indices were lacking. (shrink)

In the late sixteenth century a number of mathematicians tried to introduce geometrical methods into surveying practice, to be based on simplified astronomical instruments, angle measurement, and triangulation. A measure of success is indicated by the acceptance of the simple theodolite, but the surveyors resisted such complex instruments as the altazimuth theodolite, recipiangle, and trigonometer. Counter-proposals, in particular the plane table, threatened to undermine the geometrical programme, but by the mid-seventeenth century a stable compromise had evolved. Among other things, the (...) demise of the shadow square indicates that angle measurement was then part of surveying practice. (shrink)

As Astronomer Royal from 1835 till 1881, G. B. Airy had a very important influence on nineteenth-century British astronomy. His personal qualities combined with his office to give him a position of great authority within the astronomical and general scientific communities, and his powers of organization and work on instrumentation transformed the Royal Observatory. A feature of Airy's work was an extensive interest in horology—particularly in astronomical regulators, marine chronometers and driving clocks for chronographs and equatorial telescopes. He was also (...) concerned with building important turret clocks, and he established a public time service based at Greenwich. The enormous quantity of surviving material makes a complete review of Airy's career a daunting prospect; but the horology is a microcosm, where we can study on a manageable scale his attitudes to the Observatory, to its relation to society, and to the role of the Astronomer Royal as a public servant. (shrink)

Kinetic models using enzyme kinetics are developed for the three ways that Louie proved that Rosen’s minimal (M-R)-System can be closed to efficient cause; i.e., how the “replication” component can itself be entailed from within the system. The kinetic models are developed using the techniques of network thermodynamics. As a demonstration, each model is simulated using a SPICE circuit simulator using arbitrarily chosen rate constants. The models are built from SPICE sub-circuits representing the key terms in the chemical rate equations. (...) The models include the addition of an ad hoc semi-permeable membrane so the system can achieve steady state fluxes and also to illustrate the need for all the efficient cause agents to be continually replaced. Comments are made about exactly what is being simulated. (shrink)

We define and study the class of all stack algebras as the class of all minimal algebras in a variety defined by an infinite recursively enumerable set of equations. Among a number of results, we show that the initial model of the variety is computable, that its equational theory is decidable, but that its equational deduction problem is undecidable. We show that it cannot be finitely axiomatised by equations, but it can be finitely axiomatised by equations with a hidden sort (...) and functions. This class of all stack algebras, together with its specifications, can be used to survey the many models in the literature on stacks in a systematic way, and hence give the study of the stack some mathematical coherence. Article Outline. (shrink)

Precipitated largely by publication of the Theodicy in 1706, requests for a systematic exposition of Leibniz’s philosophy led to his self-described Éclaircissement sur les monades, begun in the summer of 1714 at the request of Remond. Unlike the treatise on philosophical theology, Leibniz’s Monadology is at once broadly systematic but sketchy and compressed: so it is useful, but then not so useful, as an introduction to his philosophy. Leibniz later decompressed it somewhat by adding references to the Theodicy, where certain (...) issues received fuller treatment. Rescher’s new book goes several steps further, still reckoning Leibniz as his own best commentator: in addition to those passages from the Theodicy, other passages from the Leibniz corpus are brought alongside each section of the Monadology, letting them pretty much speak for themselves about the ideas of that section, with a miminum of added commentary. This is a swell idea, and I think Rescher succeeds in executing it. The result is a useful work for students, who in a single edition get Leibniz’s original effort at carving his system at its joints—the principles of philosophy, he called them—and enough additional text to flesh out a full-bodied picture of his mature philosophy. (shrink)

By now widely read, Catherine Wilson’s book on Leibniz’s metaphysics needs no introduction to Leibniz scholars. This volume, like its companions in the ‘Studies in Intellectual History and the History of Philosophy’ series, succeeds in meeting high standards of historical and textual scholarship; of special note are Wilson’s remarkable grasp of the contribution that relatively minor figures made to Leibniz’s thought, and her familiarity with the European secondary literature. The book is, as a consequence, broader and historically richer than other (...) books on Leibniz in English. Contributing to this historical flavor is also a more strategic feature of Wilson’s project—namely its exploration of Leibniz’s metaphysics “[not] as a collection of theses and principles, but developmentally and thematically”. The distinction seems to imply that while one could view Leibniz’s metaphysics as a collection of principles and theses, exactly “which principles and theses?” threatens to get wrongly answered: the “governing assumption” of a developmental approach is that “what the words of a [long-dead philosopher] mean cannot be determined by an internal inspection of the texts”. Or anyway, not precisely determined, with a high confidence of Leibniz’s intentions, and for some projects this may well matter. Surely it may well matter for someone inclined—as Wilson is not—to see the largest part of Leibniz’s metaphysics as a relatively unified system of theses and principles: the governing assumption, which beckons us to read Leibniz against the backdrop of his ancient, medieval, and modern heritage, is consistent with exploring the internal coherence of the theses and principles making up his metaphysical system. If much of the older secondary literature was mistaken in doing almost to the exclusion of, Wilson’s book can scarcely be charged with the same mistake. Were I asked to complain about Wilson’s approach, I would only suggest that her eagerness and ability to do has sometimes obscured the extent to which an internal inspection of the texts is needed in fairly doing. (shrink)

Considering only exchange forces, the binding energies and excited states of nuclei up to 24 Mg are predicted to within charge independence, and there is no reason why the model should not be extended to cover all of the elements. A comparison of theory with experiment shows that the energy of one exchange is 2.56 MeV. Moreover, there is an attractive well of depth 30 MeV, corresponding to the helium nucleus, before exchange forces become operative. A possible explanation of the (...) origin of mesons is also presented. (shrink)

Mr. E. Courtney adopts Ellis's defence of repetitque, argues convincingly as a consequence that sed must be replaced by a verb, and claims: ‘That verb can hardly have been any other than stat.’ He continues : ‘This will mean that Charon's boat, having ferried across the young, does not remain tied up at the quay forgetful of the old, but goes back for them.’ The difficulty of que in the sense of sed in the line as reconstituted is defended by (...) a reference to Housman's note on Manilius, 1. 877. Still, the proposed line, non oblita tamen stat, repetitque senes, does not seem to be clear without a pause after stat, so that the reader will construe non with stat but not with repetit. This gives a very awkward rhythm indeed. (shrink)

Meges, ruler of the men of Dulichium and the Echinades, is a personage who has occasioned some trouble to the commentators on the Iliad. The difficulties are stated fully, perhaps over-fully, by Walter Leaf.